Thursday, October 22, 2020
Home COVID-19 News 'Long COVID' linked to organ impairment in young people without pre-existing conditions:...

‘Long COVID’ linked to organ impairment in young people without pre-existing conditions: Study

London, Oct 18 : Scientists, including one of Indian-origin, have assessed more than 200 people infected with the novel coronavirus and found that there was significant evidence of heart, lung, liver and pancreas impairment four months post-COVID-19 in young individuals without risk factors or pre-existing disease.

The yet-to-be peer-reviewed study, published in the preprint repository medRxiv, assessed 201 individuals enrolled at two UK sites — Perspectum, Oxford and Mayo Clinic Healthcare, London — following infection with the novel coronavirus between April and September 2020.

According to the researchers, including Sandeep Kapur from Mayo Clinic Healthcare, the average age of the participants was 44, and they completed the assessments 105-160 days after initial symptoms.

They said the prevalence of pre-existing conditions such as obesity and hypertension was low among the participants, and only 18 per cent of the individuals had been hospitalised with COVID-19.

Nearly four months after the initial symptoms, the study found that the participants still reported fatigue, muscle aches, breathlessness, and headaches.

In this low-risk population with persisting “long COVID” symptoms, almost 70 per cent of the individuals have impairment in one or more organs, four months after initial symptoms of the coronavirus infection, the researchers said.

“In this young cohort with low prevalence of comorbidities, the extent of symptom burden and organ impairment is concerning,” the scientists noted in the study.

Months after the initial symptoms were reported, the participants still experienced ongoing cardiorespiratory (92 per cent) and gastrointestinal (73 per cent) symptoms, and 42 per cent of individuals had ten or more symptoms, they said.

According to the researchers, there was evidence of mild organ impairment in heart (32 per cent), lungs (33 per cent), kidneys (12 per cent), 63 liver (10 per cent), pancreas (17 per cent), and spleen (6 per cent).

“Single and multi-organ impairment was observed, and was significantly associated with risk of prior COVID-19 hospitalisation,” the scientists wrote in the study.

Citing the limitations of the study, the researchers said the cause-effect relationship between organ impairment and infection could not be deduced, “but may be addressed by longitudinal follow-up of individuals with organ impairment.”

They added that the study population was limited by ethnicity despite disproportionate impact of COVID-19 in non-white individuals.

However, the researchers believe the findings have implications not only for the burden of long COVID but also for public health approaches which have assumed low risk in young people with no comorbidities.

“There is urgent need for further multi-organ assessment, including blood and imaging analysis in the COVID-19 context, as well as linkage with primary and secondary care data, so that long COVID can be properly defined,” the researchers noted in the study.

SourcePTI

LEAVE A REPLY

Please enter your comment!
Please enter your name here

LATEST POST

Perhaps people will design and consume more consciously: Pankaj & Nidhi on fashion during COVID-19

New Delhi, Oct 22: Pandemic has come with a lot of reality checks and Pankaj Ahuja of husband and wife designer duo Pankaj &...

Festive sales bring cheer among retailers; e-commerce players enjoy higher pie

Kolkata, Oct 22 : A buying spree among consumers during the current festive season has ushered in green shoots of recovery in the retail...

Pak resorted to 3,800 ceasefire violations along LoC this year: MEA

New Delhi, Oct 22 : Pakistani troops have resorted to more than 3,800 incidents of unprovoked ceasefire violations along the Line of Control (LoC)...

Pakistan’s apex court adjourns Daniel Pearl murder case for 4 weeks

Islamabad, Oct 22: Pakistan's apex court on Thursday adjourned for four weeks the hearing of an appeal against the acquittal of British-born al-Qaeda leader...

MOST READ

Maha will have take to loan to help flood-hit people: Pawar

Mumbai, Oct 19 : NCP chief Sharad Pawar on Monday said Maharashtra is facing a "historic economic crisis" and the state government has no...

Rajya Sabha member flags concerns over high airfares on Gulf, other routes

New Delhi, Oct 20 : Rajya Sabha member M V Shreyams Kumar has urged Civil Aviation Minister Hardeep Singh Puri to immediately look into...

Thai authorities seek to censor coverage of student protests

Bangkok, Oct 19 : Thailand's embattled prime minister said on Monday that there were no plans to extend a state of emergency outside the...

BMC withdraws sealing order of BJP MP s office

Bhubaneswar, Oct 17 : The Bhubaneswar Municipal Corporation (BMC) on Saturday withdrew its order for sealing the office of Bhubaneswar MP and BJP National...